Oncolytics stock leaps 30% as drug shrinks tumours
Oncolytics Biotech saw its stock leap nearly 30% on Friday after reporting promising mid-stage data from its flagship experimental cancer drug.
A
Phase II trial investigating the use of Reolysin in patients with small
cell lung cancer has raised hopes of a potential new treatment for the
condition, of which there are around 230,000 new cases in the US alone
every year.
Data
showed that 95% of evaluable patients (19 out of 20) given the drug in
combination with carboplatin and paclitaxel exhibited overall tumour
shrinkage by a mean of 33.3%.
Commenting on the findings, the firm's president and chief executive Brad Thompson said it
is "exciting to have 95% of patients in this study exhibit tumour
shrinkage and these results further suggest that Reolysin may have
potential use in neoadjuvant (pre-surgical) settings".
Based
on these results, the company will continue to assess the drug for lung
cancers and cancers that spread to the lung, he added.
Reolysin
is a proprietary variant of the reovirus, which is widely found in the
environment and replicates well within certain cancer lines. The drug is
being tested in various cancers, including in an ongoing Phase III
clinical trial for head and next cancer.
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